产品货号:
Z12582
中文名称:
Caspase 9/CASP9抗体
英文名称:
Anti-Caspase 9/CASP9 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Caspase 9/CASP9 Antibody |
指标别名 | APAF 3;APAF3;Apoptotic protease Mch 6;CASP 9;CASP9;Caspase 9;Caspase 9/p35/p10;CASPASE 9c;Caspase9;Caspase-9;ICE LAP6;ICE like apoptotic protease 6;MCH6 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,ICC,IF,IP |
基因名称 | CASP9 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Anti-Caspase 9 antibody was raised against a peptide corresponding to 20 amino acids near the center of human Caspase 9.The immunogen is located within amino acids 290-340 of Caspase 9. |
计算分子量 | 46kDa |
成分 | Caspase-9 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Caspase-9 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.A novel member in the caspase family was recently identified and designated ICE-LAP6,Mch6,and Apaf-3.Caspase-9 and Apaf-1 bind to each other,which leads to caspase-9 activation.Caspase-9 is also activated by granzyme B and CPP32.Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases,being responsible for the proteolytic cleavage of many key proteins in apoptosis.Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNF汐,TRAIL,anti-CD-95,FADD,and TRADD.Caspase-9 is expressed in a variety of human tissues. |
Uniprot ID | P55211 |
基因名全称 | Caspase 9,apoptosis-related cysteine peptidase |
蛋白名全称 | Caspase 9,apoptosis-related cysteine peptidase |
推荐稀释比 | WB:1μg/mL;ICC:2~ 5μg/mL;IF:5~20μg/mL.Antibody validated:Western Blot in human and mouse samples,Immunocytochemistry,Immunofluorescence in human samples.All other applications and species not yet tested. |
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